Title : Cyclooxygenase 2 inhibition exacerbates palmitate-induced inflammation and insulin resistance in skeletal muscle cells.

Pub. Date : 2010 Feb

PMID : 20022932






2 Functional Relationships(s)
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1 Coincubation of palmitate-exposed cells with oleate also prevented the increase in the expression of TLR-2 and COX-2, through a mechanism that may involve activation of peroxisome proliferator-activated receptor-alpha (PPAR alpha) by this monounsaturated fatty acid. Oleic Acid peroxisome proliferator activated receptor alpha Homo sapiens
2 Coincubation of palmitate-exposed cells with oleate also prevented the increase in the expression of TLR-2 and COX-2, through a mechanism that may involve activation of peroxisome proliferator-activated receptor-alpha (PPAR alpha) by this monounsaturated fatty acid. Oleic Acid peroxisome proliferator activated receptor alpha Homo sapiens