Title : Identification and characterisation of 2-aminopyridine inhibitors of checkpoint kinase 2.

Pub. Date : 2010 Jan 15

PMID : 20022510






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Rapid exploration of the hits through straightforward chemistry established structure-activity relationships and a proposed ATP-competitive binding mode which was verified by X-ray crystallography of several analogues bound to CHK2. Adenosine Triphosphate checkpoint kinase 2 Homo sapiens