Title : Identification and characterisation of 2-aminopyridine inhibitors of checkpoint kinase 2.

Pub. Date : 2010 Jan 15

PMID : 20022510






1 Functional Relationships(s)
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1 The 3-(4-carboxamidophenyl) substituent could be successfully replaced by acyclic omega-aminoalkylamides, which made additional polar interactions within the binding site and led to more potent inhibitors of CHK2. 4-carboxamidophenyl checkpoint kinase 2 Homo sapiens