Pub. Date : 1991 Feb 26
PMID : 2001700
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Two different metabolic alterations in vitamin A status are known to cause changes in the amount of circulating retinol-binding protein (RBP) and cellular retinol-binding protein (CRBP) in experimental animals; namely vitamin A deficiency, characterized by depleted retinol-liver stores and hypervitaminosis A, characterized by hepatic accumulation of retinyl esters. | Vitamin A | retinol binding protein 1 | Rattus norvegicus |
2 | We have found a threefold decrease in the hepatic level of CRBP mRNA in vitamin-A-deficient animals, while the RBP mRNA is not affected by this nutritional deprivation. | Vitamin A | retinol binding protein 1 | Rattus norvegicus |
3 | The results are discussed in terms of retinol-dependent stabilization of the mRNA coding for CRBP. | Vitamin A | retinol binding protein 1 | Rattus norvegicus |