Title : Interleukin-6 autoantibodies are involved in the pathogenesis of a subset of type 2 diabetes.

Pub. Date : 2010 Mar

PMID : 20016056






2 Functional Relationships(s)
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1 Mice with very high plasma levels of aAb-IL6 developed elevated fasting plasma glucose (mM, 4.8+/-0.4 vs 3.3+/-0.1, P<0.001) and impaired glucose tolerance (AUC glucose, 1340+/-38 vs 916+/-25, P<0.001) as compared with sham-control mice on normal chow. Glucose interleukin 6 Homo sapiens
2 Mice with very high plasma levels of aAb-IL6 developed elevated fasting plasma glucose (mM, 4.8+/-0.4 vs 3.3+/-0.1, P<0.001) and impaired glucose tolerance (AUC glucose, 1340+/-38 vs 916+/-25, P<0.001) as compared with sham-control mice on normal chow. Glucose interleukin 6 Homo sapiens