Title : Pharmacokinetic interaction between oral lovastatin and verapamil in healthy subjects: role of P-glycoprotein inhibition by lovastatin.

Pub. Date : 2010 Mar

PMID : 20012601






1 Functional Relationships(s)
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1 CONCLUSION: Lovastatin increased the absorption of verapamil by inhibiting P-gp and inhibited the first-pass metabolism of verapamil by inhibiting CYP3A4 in the intestine and/or liver in humans. Lovastatin cytochrome P450 family 3 subfamily A member 4 Homo sapiens