Title : Hepatic CYP2A6 levels and nicotine metabolism: impact of genetic, physiological, environmental, and epigenetic factors.

Pub. Date : 2010 Mar

PMID : 20012030






2 Functional Relationships(s)
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1 RESULTS: Liver samples with variant CYP2A6 alleles had significantly lower CYP2A6 protein expression, nicotine C-oxidation activity, and affinity for nicotine. Nicotine cytochrome P450 family 2 subfamily A member 6 Homo sapiens
2 RESULTS: Liver samples with variant CYP2A6 alleles had significantly lower CYP2A6 protein expression, nicotine C-oxidation activity, and affinity for nicotine. Nicotine cytochrome P450 family 2 subfamily A member 6 Homo sapiens