Title : Cytochalasin D, LY294002 and olomoucine synergize in promoting death of melanoma cells through activation of caspase-3 and apoptosis.

Pub. Date : 2010 Feb

PMID : 20010439






3 Functional Relationships(s)
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1 Cytochalasin D, LY294002 and olomoucine synergize in promoting death of melanoma cells through activation of caspase-3 and apoptosis. Cytochalasin D caspase 3 Homo sapiens
2 We tested cell viability, terminal dUTP nick-end labeling and activation of caspase-3 upon exposure to cytochalasin D, LY294002 and olomoucine, added either alone or in various combinations. Cytochalasin D caspase 3 Homo sapiens
3 In particular, the triple combination of cytochalasin D+LY294002+olomoucine was almost as effective as staurosporine in inducing caspase-3 activity and apoptosis. Cytochalasin D caspase 3 Homo sapiens