Title : Hot-spot mutations in p110alpha of phosphatidylinositol 3-kinase (pI3K): differential interactions with the regulatory subunit p85 and with RAS.

Pub. Date : 2010 Feb 1

PMID : 20009532






1 Functional Relationships(s)
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Protein Name
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1 In contrast, the kinase domain mutation is active in the absence of RAS-Gtp binding, but depends on the interaction with p85. Radium phosphoinositide-3-kinase regulatory subunit 1 Homo sapiens