Pub. Date : 2010 Mar 15
PMID : 20006635
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Arsenite suppression of involucrin transcription through AP1 promoter sites in cultured human keratinocytes. | arsenite | Fos proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 2 | While preserving keratinocyte proliferative ability, arsenite suppresses cellular differentiation markers by preventing utilization of AP1 transcriptional response elements. | arsenite | Fos proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 3 | In present experiments, arsenite had a dramatic effect in electrophoretic mobility supershift analysis of proteins binding to an involucrin promoter AP1 response element. | arsenite | Fos proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 4 | Immunoblotting of cell extracts showed that arsenite treatment prevented the loss of Fra1 and the increase in c-Fos proteins that occurred after confluence in untreated cultures. | arsenite | Fos proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |