Title : Evodiamine-induced human melanoma A375-S2 cell death was mediated by PI3K/Akt/caspase and Fas-L/NF-kappaB signaling pathways and augmented by ubiquitin-proteasome inhibition.

Pub. Date : 2010 Apr

PMID : 20005289






1 Functional Relationships(s)
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1 We have previously reported that evodiamine has a marked inhibitory effect on IL-1 sensitive human melanoma A375-S2 cells proliferation, and this action might be through inactivation of PI3K signaling. evodiamine interleukin 1 alpha Homo sapiens