Title : The UV-filter benzophenone-1 inhibits 17beta-hydroxysteroid dehydrogenase type 3: Virtual screening as a strategy to identify potential endocrine disrupting chemicals.

Pub. Date : 2010 Apr 15

PMID : 20005209






1 Functional Relationships(s)
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1 The database was screened using pharmacophores of 17beta-hydroxysteroid dehydrogenase type 3 (17beta-HSD3), which catalyzes the last step of testosterone synthesis in testicular Leydig cells and plays an essential role during male sexual development. Testosterone hydroxysteroid 11-beta dehydrogenase 1 like Homo sapiens