Pub. Date : 2009 Dec
PMID : 20004762
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The CHST14 gene encodes N-acetylgalactosamine 4-O-sulfotransferase 1 (D4ST1), which catalyzes 4-O sulfation of N-acetylgalactosamine in the repeating iduronic acid-alpha1,3-N-acetylgalactosamine disaccharide sequence to form dermatan sulfate. | Dermatan Sulfate | carbohydrate sulfotransferase 14 | Homo sapiens |
| 2 | The CHST14 gene encodes N-acetylgalactosamine 4-O-sulfotransferase 1 (D4ST1), which catalyzes 4-O sulfation of N-acetylgalactosamine in the repeating iduronic acid-alpha1,3-N-acetylgalactosamine disaccharide sequence to form dermatan sulfate. | Dermatan Sulfate | carbohydrate sulfotransferase 14 | Homo sapiens |
| 3 | Mass spectrometry of glycosaminoglycans from a patient"s fibroblasts revealed absence of dermatan sulfate and excess of chondroitin sulfate, showing that 4-O sulfation by CHST14 is essential for dermatan sulfate formation in vivo. | Dermatan Sulfate | carbohydrate sulfotransferase 14 | Homo sapiens |