Title : Effect of rapid human N-acetyltransferase 2 haplotype on DNA damage and mutagenesis induced by 2-amino-3-methylimidazo-[4,5-f]quinoline (IQ) and 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline (MeIQx).

Pub. Date : 2010 Feb 3

PMID : 20004212






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Bioactivation includes N-hydroxylation catalyzed by cytochrome P4501A2 (CYP1A2) followed by O-acetylation catalyzed by N-acetyltransferase 2 (NAT2). Nitrogen cytochrome P450 family 1 subfamily A member 2 Homo sapiens
2 Bioactivation includes N-hydroxylation catalyzed by cytochrome P4501A2 (CYP1A2) followed by O-acetylation catalyzed by N-acetyltransferase 2 (NAT2). Nitrogen cytochrome P450 family 1 subfamily A member 2 Homo sapiens