Title : The mechanism of distinct diurnal variations of renin-angiotensin system in aorta and heart of spontaneously hypertensive rats.

Pub. Date : 2009 Nov

PMID : 20001455






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Treatment with AT1 receptor antagonist candesartan increased plasma Ang II concentration except at ZT 8 and lessened its diurnal variation in the SHR. candesartan angiotensin II receptor, type 1a Rattus norvegicus
2 Candesartan treatment increased AT1a receptor mRNA expression in the heart but not in the aorta of SHR. candesartan angiotensin II receptor, type 1a Rattus norvegicus