Title : TiCl4-promoted Baylis-Hillman reaction: mechanistic rationale toward product distribution and stereoselectivity.

Pub. Date : 2010 Jan 15

PMID : 20000733






1 Functional Relationships(s)
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1 The diastereoselectivity in the next step, i.e., Ti-mediated aldol reaction between the enolate and aldehyde, is found to be dependent on the geometry of the enolate, wherein anti and syn BH products are predicted for Z and E enolates, respectively. Aldehydes synemin Homo sapiens