Pub. Date : 2009
PMID : 19997842
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | RESULTS: During the follow-up period of 4-12 weeks, LDL-C levels were reduced by a median of 27-31% of baseline values (mean 153.1 +/- 33.5 mg/dl) mainly regardless of previous statin therapy (rosuvastatin, atorvastatin, simvastatin, pravastatin, fluvastatin, and lovastatin) and dosing (pooled median values). | Simvastatin | component of oligomeric golgi complex 2 | Homo sapiens |
2 | LDL-C reduction correlated proportional with baseline LDL-C values and increased with increasing simvastatin dosage. | Simvastatin | component of oligomeric golgi complex 2 | Homo sapiens |
3 | CONCLUSIONS: The fixed combination therapy with ezetimibe/simvastatin showed a clinically significant additional lipid-lowering potential as compared with established statin monotherapies and enabled more patients at cardiovascular risk to reach the LDL-C target level of <100 mg/dl. | Simvastatin | component of oligomeric golgi complex 2 | Homo sapiens |