Title : Interaction of neuropeptide Y and the sympathetic nervous system in vascular control in man.

Pub. Date : 1991 Mar

PMID : 1999028






3 Functional Relationships(s)
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Compound Name
Protein Name
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1 NPY coexists with noradrenaline in perivascular nerve terminals, may be released during sympathetic stimulation, and is a potent constrictor of the human coronary circulation and other vascular beds. Norepinephrine neuropeptide Y Homo sapiens
2 In vitro studies show that NPY can act either directly on vascular smooth muscle or indirectly by modulation of the presynaptic release or the postsynaptic actions of noradrenaline. Norepinephrine neuropeptide Y Homo sapiens
3 METHODS AND RESULTS: The effect on forearm blood flow of intra-arterial NPY was studied in six volunteers during coinfusion of noradrenaline and during reflex sympathetic stimulation induced by lower-body negative pressure. Norepinephrine neuropeptide Y Homo sapiens