Title : Acute effect of the anti-addiction drug bupropion on extracellular dopamine concentrations in the human striatum: an [11C]raclopride PET study.

Pub. Date : 2010 Mar

PMID : 19969097






2 Functional Relationships(s)
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1 Bupropion inhibits striatal dopamine reuptake via dopamine transporter blockade, but it is unknown whether this leads to increased extracellular dopamine levels at clinical doses in man. Bupropion solute carrier family 6 member 3 Homo sapiens
2 Levels of dopamine transporter occupancy in the rat at 11 and 25 mg/kg bupropion i.p. Bupropion solute carrier family 6 member 3 Homo sapiens