Title : 1-Nitropyrene stabilizes the mRNA of cytochrome P450 1a1, a carcinogen-metabolizing enzyme, via the Akt pathway.

Pub. Date : 2009 Dec

PMID : 19961161






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 When Cyp1a1"s turnover was examined, 1-NP was able to stabilize the 1-NP- and benzo[a]pyrene (BaP)-induced Cyp1a1 mRNA, but not protein. Benzo(a)pyrene cytochrome P450 family 1 subfamily A member 1 Homo sapiens
2 When Cyp1a1"s turnover was examined, 1-NP was able to stabilize the 1-NP- and benzo[a]pyrene (BaP)-induced Cyp1a1 mRNA, but not protein. Benzo(a)pyrene cytochrome P450 family 1 subfamily A member 1 Homo sapiens
3 When Cyp1a1"s turnover was examined, 1-NP was able to stabilize the 1-NP- and benzo[a]pyrene (BaP)-induced Cyp1a1 mRNA, but not protein. Benzo(a)pyrene cytochrome P450 family 1 subfamily A member 1 Homo sapiens