Title : Human AlkB homologue 1 (ABH1) exhibits DNA lyase activity at abasic sites.

Pub. Date : 2010 Jan 2

PMID : 19959401






1 Functional Relationships(s)
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Protein Name
Organism
1 The DNA cleavage activity of ABH1 does not require added Fe(2+) or 2-oxoglutarate, is not inhibited by EDTA, and is unaffected by mutation of the putative metal-binding residues, indicating that this activity arises from an active site distinct from that used for demethylation. ammonium ferrous sulfate alkB homolog 1, histone H2A dioxygenase Homo sapiens