Pub. Date : 2010 Mar 10
PMID : 19958758
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Involvement of the 5-HT(1A) receptor in the anti-immobility effects of fluvoxamine in the forced swimming test and mouse strain differences in 5-HT(1A) receptor binding. | Fluvoxamine | 5-hydroxytryptamine (serotonin) receptor 1A | Mus musculus |
| 2 | The anti-immobility effects of fluvoxamine in DBA/2 mice were inhibited by the 5-HT(1A) receptor antagonist N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl)cyclohexanecarboxamide (WAY 100635). | Fluvoxamine | 5-hydroxytryptamine (serotonin) receptor 1A | Mus musculus |
| 3 | These results suggest that fluvoxamine-induced antidepressant-like effects in DBA/2 mice are mediated by the 5-HT(1A) receptor. | Fluvoxamine | 5-hydroxytryptamine (serotonin) receptor 1A | Mus musculus |
| 4 | These results suggest that, although the anti-immobility effects of fluvoxamine in DBA/2 mice are mediated by the 5-HT(1A) receptor, strain differences in 5-HT(1A) receptor binding are not related to variation in immobility time and responses to fluvoxamine. | Fluvoxamine | 5-hydroxytryptamine (serotonin) receptor 1A | Mus musculus |