Title : RIAM regulates the cytoskeletal distribution and activation of PLC-gamma1 in T cells.

Pub. Date : 2009 Dec 1

PMID : 19952372






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 These events were associated with the impaired translocation of phosphorylated phospholipase C-gamma1 (PLC-gamma1) to the actin cytoskeleton, which was required to bring PLC-gamma1 close to its substrate phosphatidylinositol 4,5-bisphosphate, and were reversed by reconstitution of cells with RIAM. Phosphatidylinositol 4,5-Diphosphate phospholipase C gamma 1 Homo sapiens
2 These events were associated with the impaired translocation of phosphorylated phospholipase C-gamma1 (PLC-gamma1) to the actin cytoskeleton, which was required to bring PLC-gamma1 close to its substrate phosphatidylinositol 4,5-bisphosphate, and were reversed by reconstitution of cells with RIAM. Phosphatidylinositol 4,5-Diphosphate phospholipase C gamma 1 Homo sapiens