Title : Folate receptor beta is expressed by tumor-associated macrophages and constitutes a marker for M2 anti-inflammatory/regulatory macrophages.

Pub. Date : 2009 Dec 15

PMID : 19951991






1 Functional Relationships(s)
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1 The acquisition of folate uptake ability by macrophages is promoted by M-CSF, maintained by IL-4, prevented by GM-CSF, and reduced by IFNgamma, indicating a link between FRbeta expression and M2 polarization. Folic Acid colony stimulating factor 2 Homo sapiens