Title : Ibuprofen: pharmacology, efficacy and safety.

Pub. Date : 2009 Dec

PMID : 19949916






1 Functional Relationships(s)
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1 (3) The multiple actions of ibuprofen in controlling inflammation combine with moderate inhibition of COX-1 and COX-2 and low residence time of the drug in the body may account for the low GI, CV and renal risks from ibuprofen, especially at OTC doses. Ibuprofen mitochondrially encoded cytochrome c oxidase II Homo sapiens