Title : Expression analysis of maspin in invasive ductal carcinoma of breast and modulation of its expression by curcumin in breast cancer cell lines.

Pub. Date : 2010 Feb 12

PMID : 19944674






1 Functional Relationships(s)
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1 Curcumin inhibited cell growth, induced apoptosis and upregulated maspin gene expression in MCF-7 cells and these findings were further correlated with the upregulation of p53 protein and downregulation of Bcl-2, suggesting maspin mediated apoptosis in MCF-7 cells. Curcumin tumor protein p53 Homo sapiens