Title : Intrarenal cytochrome P-450 metabolites of arachidonic acid in the regulation of the nonclipped kidney function in two-kidney, one-clip Goldblatt hypertensive rats.

Pub. Date : 2010 Mar

PMID : 19940786






1 Functional Relationships(s)
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1 OBJECTIVE: The contribution of epoxyeicosatrienoic acids (EETs) and 20-hydroxyeicosatetraenoic acid (20-HETE) as cytochrome P-450 metabolites of arachidonic acid in the regulation of the nonclipped kidney function in two-kidney, one-clip (2K1C) Goldblatt hypertensive rats was investigated during the phases of initial and stable hypertension, that is, 7 or 27 days after clipping, respectively. epoxyeicosatrienoic acids cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus