Pub. Date : 2010 Feb
PMID : 19940100
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Leucine (2 mM, 30 min) significantly enhanced contraction-stimulated 3-MG transport and AMPK phosphorylation, accompanied by increased phosphorylation of p70 S6 kinase (p70S6K) Thr(389). | Leucine | ribosomal protein S6 kinase B1 | Rattus norvegicus |
| 2 | Leucine (2 mM, 30 min) significantly enhanced contraction-stimulated 3-MG transport and AMPK phosphorylation, accompanied by increased phosphorylation of p70 S6 kinase (p70S6K) Thr(389). | Leucine | ribosomal protein S6 kinase B1 | Rattus norvegicus |
| 3 | The stimulatory effects of leucine on 3-MG transport and AMPK phosphorylation were canceled by STO-609 blockade of Ca(2+)/calmodulin-dependent protein kinase kinase (CaMKK) or rapamycin blockade of p70S6K. | Leucine | ribosomal protein S6 kinase B1 | Rattus norvegicus |
| 4 | Leucine increased insulin-stimulated p70S6K Thr(389) phosphorylation and enhanced the inhibitory phosphorylation of the insulin receptor substrate 1 (IRS1) Ser(636/639). | Leucine | ribosomal protein S6 kinase B1 | Rattus norvegicus |