Title : A common mutation of the MYH gene is associated with increased DNA oxidation and age-related diseases.

Pub. Date : 2010 Feb 1

PMID : 19932167






2 Functional Relationships(s)
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1 We describe a common mutation of the MYH gene, which is involved in the repair of oxidative damage to DNA, and its relationship to age, levels of 8-OHdG, and circulating levels of interleukin-1. 8-ohdg mutY DNA glycosylase Homo sapiens
2 Because the MYH gene is involved in DNA repair we assessed whether homozygous carriage of this gene was associated with increased levels of 8-OHdG in the leukocytic DNA of carriers. 8-ohdg mutY DNA glycosylase Homo sapiens