Title : Bile acid-activated receptors in the treatment of dyslipidemia and related disorders.

Pub. Date : 2010 Apr

PMID : 19932133






1 Functional Relationships(s)
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1 Primary bile acids (chenodeoxycholic acid and cholic acid) are physiological ligands/activators of farnesoid-X-receptor (FXR), pregnane-X-receptor (PXR) and constitutive androstane receptor (CAR), while litocholic acid is a ligand for the Vitamin D receptor (VDR) and the G-protein coupled receptor TGR5. Lithocholic Acid nuclear receptor subfamily 1 group I member 3 Homo sapiens