Title : Intermonomer interactions are essential for lysosomal enzyme binding by the cation-dependent mannose 6-phosphate receptor.

Pub. Date : 2010 Jan 12

PMID : 19928875






1 Functional Relationships(s)
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1 The 46 kDa cation-dependent mannose 6-phosphate receptor (CD-MPR) plays a key role in the delivery of lysosomal enzymes to the lysosome by binding newly synthesized mannose 6-phosphate (Man-6-P)-containing acid hydrolases and diverting them from the secretory pathway. mannose-6-phosphate mannose-6-phosphate receptor, cation dependent Homo sapiens