Title : Tissue factor mediates the HGF/Met-induced anti-apoptotic pathway in DAOY medulloblastoma cells.

Pub. Date : 2010 May

PMID : 19921488






2 Functional Relationships(s)
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1 In this study, we report that stimulation of DAOY with HGF resulted in the protection of these cells against etoposide-induced apoptosis, this anti-apoptotic effect being correlated with an increase in the expression of tissue factor (TF), the initiator of the extrinsic pathway of coagulation. Etoposide coagulation factor III, tissue factor Homo sapiens
2 Accordingly, stimulation of DAOY with FVIIa, the physiological ligand of TF, also resulted in a significant protection from etoposide-mediated cytotoxicity. Etoposide coagulation factor III, tissue factor Homo sapiens