Title : Pancreatic endocrine tumors: expression profiling evidences a role for AKT-mTOR pathway.

Pub. Date : 2010 Jan 10

PMID : 19917848






1 Functional Relationships(s)
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1 TSC2 and PTEN are two key inhibitors of the Akt/mammalian target of rapamycin (mTOR) pathway and the specific inhibition of mTOR with rapamycin or RAD001 inhibited cell proliferation of PET cell lines. Sirolimus phosphatase and tensin homolog Homo sapiens