Title : Connective tissue growth factor is induced in bleomycin-induced skin scleroderma.

Pub. Date : 2010 Mar

PMID : 19916059






4 Functional Relationships(s)
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1 Connective tissue growth factor is induced in bleomycin-induced skin scleroderma. Bleomycin cellular communication network factor 2 Mus musculus
2 In this report, we use an antibody recognizing CCN2 to assess the cell types in mouse dermis which express CCN2 in the bleomycin model of skin scleroderma. Bleomycin cellular communication network factor 2 Mus musculus
3 However, upon exposure to bleomycin, CCN2 was observed in the dermis. Bleomycin cellular communication network factor 2 Mus musculus
4 Moreover, CCN2-expressing pericytes significantly contribute to the appearance of myofibroblasts in bleomycin-induced skin scleroderma. Bleomycin cellular communication network factor 2 Mus musculus