Pub. Date : 2010
PMID : 19914607
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The results show that phorbol 12-myristate 13-acetate (PMA) treatment (with or without ionomycin) and serum starvation (s/s) induced sustained ERK1/2 activation in murine thymocytes. | Tetradecanoylphorbol Acetate | mitogen-activated protein kinase 3 | Mus musculus |
| 2 | The results show that phorbol 12-myristate 13-acetate (PMA) treatment (with or without ionomycin) and serum starvation (s/s) induced sustained ERK1/2 activation in murine thymocytes. | Tetradecanoylphorbol Acetate | mitogen-activated protein kinase 3 | Mus musculus |
| 3 | Importantly, pharmacological treatment of thymocytes with the MEK inhibitor UO126 revealed that PMA-induced ERK1/2 activation was proapoptotic, whereas serum starvation-induced ERK1/2 activation inhibited apoptosis and promoted cell survival. | Tetradecanoylphorbol Acetate | mitogen-activated protein kinase 3 | Mus musculus |