Title : A 5'-flanking region of the bovine tyrosine hydroxylase gene is involved in cell-specific expression, activation of gene transcription by phorbol ester, and transactivation by c-Fos and c-Jun.

Pub. Date : 1992 Oct

PMID : 19912882






2 Functional Relationships(s)
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1 Incubation of neuroblastoma cells with the active phorbol ester, phorbol 12-myristate 13-acetate (PMA), increased expression of CAT from pTH(-245/+2 1)CAT over 6-fold and was accompanied by induction of c-fos and c-jun mRNAs and proteins. Tetradecanoylphorbol Acetate Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens
2 Incubation of neuroblastoma cells with the active phorbol ester, phorbol 12-myristate 13-acetate (PMA), increased expression of CAT from pTH(-245/+2 1)CAT over 6-fold and was accompanied by induction of c-fos and c-jun mRNAs and proteins. Tetradecanoylphorbol Acetate Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens