Title : Impaired transmethylation potential in Parkinson's disease patients treated with L-Dopa.

Pub. Date : 2010 Jan 14

PMID : 19909787






2 Functional Relationships(s)
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1 Our results also support the conclusion that COMT inhibitors (entacapone or tolcapone), when administered in PD patients treated with l-Dopa, may potentiate the endogenous AdoHcy-dependent COMT inhibition mechanism already operative in a variable fashion. entacapone catechol-O-methyltransferase Homo sapiens
2 Our results also support the conclusion that COMT inhibitors (entacapone or tolcapone), when administered in PD patients treated with l-Dopa, may potentiate the endogenous AdoHcy-dependent COMT inhibition mechanism already operative in a variable fashion. entacapone catechol-O-methyltransferase Homo sapiens