Title : Co-purified gelatinases alter the stability and biological activities of human plasma fibronectin preparations.

Pub. Date : 2010 Apr

PMID : 19909400






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Preparations of FN purified from human plasma by gelatin-Sepharose affinity chromatography typically also contain gelatin-binding gelatinases that may cleave FN, reduce its stability and alter its biological activities. Sepharose fibronectin 1 Homo sapiens
2 MATERIAL AND METHODS: Experiments tested the elution profiles for FN and gelatinases from gelatin-Sepharose using a concentration range (1-7%) of dimethyl sulfoxide (DMSO) and 4 m urea as eluants. Sepharose fibronectin 1 Homo sapiens