Title : Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl.

Pub. Date : 2010 Jan 22

PMID : 19906645






2 Functional Relationships(s)
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1 Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl. Proline ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens
2 In the light of these results, a new dual binding mechanism is proposed that provides a better description of proline-rich ligand recognition by Abl-SH3 and that has important implications for rational design. Proline ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens