Pub. Date : 2010 Feb 1
PMID : 19906043
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The nucleotide sugar transporters AtUTr1 and AtUTr3 are required for the incorporation of UDP-glucose into the endoplasmic reticulum, are essential for pollen development and are needed for embryo sac progress in Arabidopsis thaliana. | Uridine Diphosphate Glucose | UDP-galactose transporter 3 | Arabidopsis thaliana |
| 2 | Here we show that AtUTr3 is involved in the transport of UDP-glucose and is located at the ER but also at the Golgi. | Uridine Diphosphate Glucose | UDP-galactose transporter 3 | Arabidopsis thaliana |
| 3 | Biochemical analysis in both AtUTr1 and AtUTr3 mutants indicates that uptake of UDP-glucose into the ER is mostly driven by these two transporters. | Uridine Diphosphate Glucose | UDP-galactose transporter 3 | Arabidopsis thaliana |
| 4 | Interestingly, the expression of AtUTr3 is induced by stimuli that trigger the unfolded protein response (UPR), a phenomenon also observed for AtUTr1, suggesting that both AtUTr1 and AtUTr3 are involved in supplying UDP-glucose into the ER lumen when misfolded proteins are accumulated. | Uridine Diphosphate Glucose | UDP-galactose transporter 3 | Arabidopsis thaliana |
| 5 | Interestingly, the expression of AtUTr3 is induced by stimuli that trigger the unfolded protein response (UPR), a phenomenon also observed for AtUTr1, suggesting that both AtUTr1 and AtUTr3 are involved in supplying UDP-glucose into the ER lumen when misfolded proteins are accumulated. | Uridine Diphosphate Glucose | UDP-galactose transporter 3 | Arabidopsis thaliana |
| 6 | These results show that the nucleotide sugar transporters AtUTr1 and AtUTr3 are required for the incorporation of UDP-glucose into the ER, are essential for pollen development and are needed for embryo sac progress in Arabidopsis thaliana. | Uridine Diphosphate Glucose | UDP-galactose transporter 3 | Arabidopsis thaliana |