Title : Development of a method to measure methadone enantiomers and its metabolites without enantiomer standard compounds for the plasma of methadone maintenance patients.

Pub. Date : 2010 Jul

PMID : 19904716






4 Functional Relationships(s)
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1 This method was established by the characteristics of recombinant cytochrome P-450 (CYP) isozymes, where CYP2C19 prefers to metabolize R-methadone and CYP2B6 prefers to metabolize S-methadone. Methadone cytochrome P450 family 4 subfamily F member 3 Homo sapiens
2 This method was established by the characteristics of recombinant cytochrome P-450 (CYP) isozymes, where CYP2C19 prefers to metabolize R-methadone and CYP2B6 prefers to metabolize S-methadone. Methadone cytochrome P450 family 4 subfamily F member 3 Homo sapiens
3 This method was established by the characteristics of recombinant cytochrome P-450 (CYP) isozymes, where CYP2C19 prefers to metabolize R-methadone and CYP2B6 prefers to metabolize S-methadone. Methadone cytochrome P450 family 4 subfamily F member 3 Homo sapiens
4 This method was established by the characteristics of recombinant cytochrome P-450 (CYP) isozymes, where CYP2C19 prefers to metabolize R-methadone and CYP2B6 prefers to metabolize S-methadone. Methadone cytochrome P450 family 4 subfamily F member 3 Homo sapiens