Title : Detection of treatment-induced changes in signaling pathways in gastrointestinal stromal tumors using transcriptomic data.

Pub. Date : 2009 Dec 1

PMID : 19903850






1 Functional Relationships(s)
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1 Pursuing these findings, we have determined that imatinib-induced DNA damage is responsible for the increased activity of p53, identifying a novel off-target activity for this drug. Imatinib Mesylate tumor protein p53 Homo sapiens