Title : Polymorphism of human cytochrome P450 2D6 and its clinical significance: part II.

Pub. Date : 2009

PMID : 19902987






2 Functional Relationships(s)
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1 A number of clinical studies have indicated that there are significant relationships between the CYP2D6 genotype and steady-state concentrations of perphenazine, zuclopenthixol, risperidone and haloperidol. Haloperidol cytochrome P450 family 2 subfamily D member 6 Homo sapiens
2 Therapeutic drug monitoring has been strongly recommended for many antipsychotics, including haloperidol, chlorpromazine, fluphenazine, perphenazine, risperidone and thioridazine, which are all metabolized by CYP2D6. Haloperidol cytochrome P450 family 2 subfamily D member 6 Homo sapiens