Title : Identification of multidrug resistance protein 1 (MRP1/ABCC1) as a molecular gate for cellular export of cobalamin.

Pub. Date : 2010 Feb 25

PMID : 19897579






1 Functional Relationships(s)
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1 The ability of MRP1 to mediate ATP-dependent Cbl transport was confirmed by vesicular transport experiments, and a physiologic role of MRP1 in mammalian Cbl homeostasis is indicated by the phenotype of knockout mice with targeted disruption of MRP1. Adenosine Triphosphate ATP binding cassette subfamily B member 1 Homo sapiens