Title : The AU-rich sequences in the 3' untranslated region mediate the increased turnover of interferon mRNA induced by glucocorticoids.

Pub. Date : 1991 Feb 1

PMID : 1988537






2 Functional Relationships(s)
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1 The synthetic glucocorticoid dexamethasone was previously shown to increase the turnover of IFN-beta mRNA. Dexamethasone interferon beta 1 Homo sapiens
2 This activity of dexamethasone was clearly observed only in cells expressing IFN-beta mRNA with AU-rich sequences in the 3" UTR. Dexamethasone interferon beta 1 Homo sapiens