Title : Paradox findings may challenge orthodox reasoning in acute organophosphate poisoning.

Pub. Date : 2010 Sep 6

PMID : 19883634






3 Functional Relationships(s)
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1 Also oxime therapy in organophosphorus poisoning apparently gives perplexing results: Oximes are usually able to reactivate diethylphosphorylated AChE, but the efficiency may be occasionally markedly smaller than expected from kinetic data. Oximes acetylcholinesterase (Cartwright blood group) Homo sapiens
2 Also oxime therapy in organophosphorus poisoning apparently gives perplexing results: Oximes are usually able to reactivate diethylphosphorylated AChE, but the efficiency may be occasionally markedly smaller than expected from kinetic data. Oximes acetylcholinesterase (Cartwright blood group) Homo sapiens
3 Dimethylphosphorylated AChE is in general less amenable to oxime therapy, which largely fails in some cases of dimethoate poisoning where aging was much faster than expected from a dimethylphosphorylated enzyme. Oximes acetylcholinesterase (Cartwright blood group) Homo sapiens