Title : Evaluation of induction potency of new drug candidates on CYP1A2 and CYP3A4 using real-time one-step RT-PCR in primary cultures of cryopreserved human hepatocytes.

Pub. Date : 2009

PMID : 19881256






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Positive controls for CYP1A2 and CYP3A4 used beta-naphthoflavone (beta-NF) and rifampicin (Rif), respectively. Rifampin cytochrome P450 family 1 subfamily A member 2 Homo sapiens
2 Positive controls for CYP1A2 and CYP3A4 used beta-naphthoflavone (beta-NF) and rifampicin (Rif), respectively. Rifampin cytochrome P450 family 1 subfamily A member 2 Homo sapiens