Title : Role of two strictly conserved residues in nucleotide flipping and N-glycosylic bond cleavage by human thymine DNA glycosylase.

Pub. Date : 2009 Dec 25

PMID : 19880517






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 TDG cleaves the N-glycosylic bond of dT and some other nucleotides, including 5-substituted 2"-deoxyuridine analogs, once they have been flipped from the helix into its active site. Thymidine thymine DNA glycosylase Homo sapiens