Pub. Date : 2009 Nov
PMID : 19876784
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Leukotriene synthesis requires 5-lipoxygenase activating protein (FLAP), which acts as a scaffolding protein for the assembly of other enzymes involved in the leukotriene synthetic pathway occurring at the nuclear envelope of leukocytes. | Leukotrienes | arachidonate 5-lipoxygenase activating protein | Homo sapiens |
| 2 | Leukotriene synthesis requires 5-lipoxygenase activating protein (FLAP), which acts as a scaffolding protein for the assembly of other enzymes involved in the leukotriene synthetic pathway occurring at the nuclear envelope of leukocytes. | Leukotrienes | arachidonate 5-lipoxygenase activating protein | Homo sapiens |
| 3 | By blocking the formation of both leukotriene B4 and the cysteinyl leukotrienes (ie, LTC4 , LTD4 and LTE4), FLAP inhibitors act as broad-spectrum leukotriene-modifier drugs that may have a wide range of therapeutic applications. | Leukotrienes | arachidonate 5-lipoxygenase activating protein | Homo sapiens |