Title : A proteomic investigation of ligand-dependent HSP90 complexes reveals CHORDC1 as a novel ADP-dependent HSP90-interacting protein.

Pub. Date : 2010 Feb

PMID : 19875381






4 Functional Relationships(s)
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1 A proteomic investigation of ligand-dependent HSP90 complexes reveals CHORDC1 as a novel ADP-dependent HSP90-interacting protein. Adenosine Diphosphate heat shock protein 90 alpha family class A member 1 Homo sapiens
2 A proteomic investigation of ligand-dependent HSP90 complexes reveals CHORDC1 as a novel ADP-dependent HSP90-interacting protein. Adenosine Diphosphate heat shock protein 90 alpha family class A member 1 Homo sapiens
3 Here we use tandem affinity purification and LC-MS/MS to investigate the proteome-wide effects of ATP, ADP, and geldanamycin on the constituents of the human HSP90 interactome. Adenosine Diphosphate heat shock protein 90 alpha family class A member 1 Homo sapiens
4 We further characterized a novel ADP-dependent HSP90 interaction with the cysteine- and histidine-rich domain (CHORD)-containing protein CHORDC1. Adenosine Diphosphate heat shock protein 90 alpha family class A member 1 Homo sapiens